A Case of Sjogren Syndrome in Parotid Gland.

Park, Jang Woo; Kim, Ho Kil; Kim, Mi Sun; Ahn, Hyung Sik; Kim, Jun Hyug; Lee, Young Man

Case Report

Journal of Korean Cleft Palate-Craniofacial Association 2007;8(1):20-22.

Jang Woo Park, Ho Kil Kim, Mi Sun Kim, Hyung Sik Ahn, Jun Hyug Kim, Young Man Lee

Department of Plastic and Reconstructive Surgery, Soonchunhyang University College of Medicine, Chunahn, Korea. psmisun@naver.com

Abstract

Sjogren syndrome is a chronic disorder characterized by immune-mediated destruction of exocrine glands predominantly but not exclusively on the lacrimal and salivary glands. The common clinical manifestations of Sjgren syndrome include xerophthalmia with secondary keratoconjunctivitis and xerostomia, with or without salivary gland enlargement. Minor salivary gland biopsy usually demonstrates heavy lymphocyte infiltration, although parotid gland biopsy may be more sensitive and specific. Rheumatoid factor and antinuclear antibodies are high in Sjgren syndrome patients. We report a case of Sjogren syndrome with parotid gland involvement in a 44-years-old female patient with xerostomia, xerophthalmia and Rheumatic arthritis. We did total parotidectomy in right parotid gland and superficial parotidectomy for left side parotid gland was done after 20 days. Histologic and immunohistochemical studies revelead multiple periductal lymphoid proliferation and chromic inflammation, lymphoid hyperplasia in parotid glands.

Keywords: Sjogren syndrome; Parotidectomy