A Case of Wegener's Granulomatosis in the Orbital Area.

Choi, Hwan Jun; Park, Eun Soo; Kang, Sang Gue; Tark, Min Sung; Kim, Yong Bae; Go, Eun Suk

Original Article

Journal of Korean Cleft Palate-Craniofacial Association 2003;4(1):71-74.

Hwan Jun Choi, Eun Soo Park, Sang Gue Kang, Min Sung Tark, Yong Bae Kim, Eun Suk Go

¹Department of Plastic and Reconstructive Surgery, College of Medicine, Soon Chun Hyang University, Seoul, Korea. medi619@hanmail.net
²Department of Pathology, College of Medicine, Soon Chun Hyang University, Seoul, Korea.

Abstract

Wegener`s granulomatosis(WG) is uncommon disease characterized by necrotizing granulomatous lesions in the both upper and lower respiratory tracts, generalized focal necrotizing vasculitis, and focal necrotizing glomerulonephritis. Other organs are also involved frequently. Ocular complications may occur secondary to contiguous granulomatous sinusitis or as a result of focal vasculitis and are encountered in 40-50% of cases of generalized form. We experienced a case of WG developed progressive paranasal sinusitis and rhinitis combined with orbital and ocular involvement. The diagnosis was confirmed by clinical findings and histopathologic features of tissue biopsy. The histopathology from periorbital area had typical findings of WG with necrotizing vasculitis and granuloma formation.

Keywords: Wegener`s Granulomatosis; Orbit